Review



biotinylated anti human pd 1 affinity  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    R&D Systems biotinylated anti human pd 1 affinity
    Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, <t>or</t> <t>PD-1</t> for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.
    Biotinylated Anti Human Pd 1 Affinity, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 40 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/biotinylated anti human pd 1 affinity/product/R&D Systems
    Average 93 stars, based on 40 article reviews
    biotinylated anti human pd 1 affinity - by Bioz Stars, 2026-03
    93/100 stars

    Images

    1) Product Images from "Defective Human Immunodeficiency Virus-Specific CD8 + T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy ▿ "

    Article Title: Defective Human Immunodeficiency Virus-Specific CD8 + T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy ▿

    Journal: Journal of Virology

    doi: 10.1128/JVI.01153-09

    Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, or PD-1 for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.
    Figure Legend Snippet: Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, or PD-1 for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.

    Techniques Used: Infection, Expressing, Functional Assay



    Similar Products

    biotinylated anti human pd 1 affinity  (R&D Systems)
    93
    R&D Systems biotinylated anti human pd 1 affinity
    Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, <t>or</t> <t>PD-1</t> for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.
    Biotinylated Anti Human Pd 1 Affinity, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/biotinylated anti human pd 1 affinity/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    biotinylated anti human pd 1 affinity - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, or PD-1 for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.

    Journal: Journal of Virology

    Article Title: Defective Human Immunodeficiency Virus-Specific CD8 + T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy ▿

    doi: 10.1128/JVI.01153-09

    Figure Lengend Snippet: Polyfunctionality and phenotype of HIV-specific CD8+ T cells following stimulation with HIV-infected CD4+ T-cell targets for 6 h. (A) Summary pie charts show median percentages of total responding CD8+ T cells that express IFN-γ, MIP-1β, CD107, IL-2, or TNF-α in LTNP (n = 23, first row) and Rx <50 (n = 47, second row). Scatter plots (third row) depict the percent expression of each function for each LTNP and Rx <50. Horizontal lines represent median values. Comparisons were made using the Wilcoxon two-sample test. Only significant P values are shown. (B) Summary pie charts (top row) show median percentages of responding CD8+ T cells grouped according to the number of simultaneous functions executed: five functions, red; four, yellow; three, green; two, blue; and one, black. Individual functional subsets are shown in the summary bar graph (bottom row) for LTNP (red) and Rx <50 (blue). Background responses to uninfected targets have been subtracted. A line extends from the median to the upper interquartile range. Asterisks indicate significant differences between response pairs: ***, P < 0.001; **, P < 0.01; and *, P < 0.05. (C) Summary pie charts (first and second rows) and scatter plots (third row) show the fraction of the total responding CD8+ T cells expressing CCR7, CD45RA, or PD-1 for the same patients as in panel A. (D) Summary pie charts and bar graph show median percentages of responding CD8+ T cells expressing various combinations of the three phenotypic markers. CCR7+ subsets are shown in shades of teal, and CCR7− subsets are shown in shades of pink.

    Article Snippet: PD-1 staining was performed using a biotinylated anti-human PD-1 affinity-purified goat immunoglobulin G primary stain (R&D Systems, Inc., Minneapolis, MN) and a Qdot 655 streptavidin conjugate as secondary stain (Invitrogen Molecular Probes).

    Techniques: Infection, Expressing, Functional Assay